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bp0010ised2 | (1) | ISED2019

A role for Msx genes in mammalian embryonic diapause

Cha J , Fenelon JC , Murphy BD , Shaw G , Renfree MB , Dey SK

Mammalian embryonic diapause is a reproductive phenomenon defined by the reversible arrest in blastocyst development and metabolic activity within the uterus which synchronously becomes quiescent to implantation. This natural strategy, evident in over 130 species across eight orders, can temporally uncouple conception from delivery until conditions are favorable for the survival of the mother and newborn. While the maternal endocrine milieu has been shown to be important for t...